Throwback: It’s Not JUST About the Science

At a time when “evidence-based” everything is all the rage; I would like to share my experience and philosophy in regard to salivary diagnostics.  My approach comes from a non-scientific perspective garnered from my 40+ years of clinical experience.  I come at it from both a trained scientific, human, psychological, patient management and pragmatic mindset. Several years back, I had a discussion with a well-respected career academic and journal editor about “evidence-based” medicine.  He ...
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Do We Really Need Antibiotics for Periodontal Disease?

When patients receive their OralDNA® MyPerioPath® test results, one of the most common questions is: “Why aren’t we prescribing antibiotics?” After all, the test identifies bacteria linked to periodontal (gum) disease. Shouldn’t antibiotics be the next step? Dr. Lee Sheldon explains that the answer often goes back to the root cause of periodontal disease itself. “Periodontal disease is the loss of support for the teeth. It comes primarily from bacteria that go below the gum line and lo...
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Throwback: Communication is Key

Periodontal disease is one of the most prevalent chronic inflammatory diseases in the United States and it is a key indicator of other systemic diseases.  Dentistry has a significant role in reducing the impact of chronic disease in patients who trust their dental teams to guide them to total body health.  From the first call and through every step of the patient experience, such as reviewing the medical history, the conversation should include the oral systemic connection. Dental teams a...
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Throwback: Side Effects Support LLC

As I started my first job in dentistry, my mother received a breast cancer diagnosis and suffered horribly with oral side effects from chemotherapy. Her pain from severe dry mouth and mouth sores (oral mucositis) was dismissed by her oncology team as “just part of treatments.” She received no guidance on how to prevent or reduce her discomfort and there were no oral care strategies implemented to prevent long-term damage to her dental health. Through questioning other cancer survivors, I le...
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Interview with Dr. Geoffrey Sharpe

Dr. Ron McGlennen: How were you introduced to OralDNA® salivary diagnostics, and what motivated you to incorporate it into your practice? Dr. Geoffrey Sharpe: As a periodontist, I had been aware of salivary diagnostic testing for some time. However, this subject was not widely taught at dental schools, even at the postgraduate level. A number of colleagues in my network were strong advocates of the tests available from OralDNA® Labs and I became curious to explore their potential in my sp...
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Beyond the Probe: How OralDNA Testing Transformed Our Protocols and Outcomes

For decades, we've understood that periodontal disease is bacterial in origin, yet many of our treatment strategies remained nonspecific. We scaled, we cleaned, we hoped for the best. OralDNA® testing changed that for us - it brought specificity, clarity, and purpose to our protocols.  At our practice, every periodontal patient and every medically high-risk patient receives an OralDNA® MyPerioPath as a baseline test. This includes individuals with diabetes, cardiovascular disease, or auto...
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Throwback: Salivary Diagnostics for Gum Disease and Oral Cancer Risk Assessment

Clinical laboratory testing is a common practice for the medical professional. DNA testing, including genetic testing, has led to healthier patients. Cross over to dentistry, and let’s review 2 examples of what’s available. Presently, in my office, we perform MyPerioID® IL-6, a test for the genetic marker interleukin 6 (IL-6) to screen for genetic risk of periodontal disease and a viral DNA test for the human papilloma virus (HPV) to screen for risk of oral cancer.  The collection is relativ...
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Protect Patient Health with Salivary Diagnostics

Persistent oral human papillomavirus (HPV) infections have been linked to an increased risk of oral and oropharyngeal cancer. According to the Center for Disease Control and Prevention (CDC), HPV is the most common sexually transmitted infection. Over 200 strains of HPV have been identified. The high-risk types, HPV-16 and HPV-18 are associated with oropharyngeal squamous cell carcinoma (OPSCC). The CDC reports that HPV is responsible for approximately 70% of oropharyngeal cancer in the Unit...
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The Hidden Threat to Dental Implants: Why Ignoring Bacteria is a Risky Gamble – Part 2

  In Part 1, we uncovered a hidden threat to dental implants—bacteria—and explored why so many providers overlook the critical step of testing for harmful pathogens before placement. Despite the clear risks, common objections like cost, insurance coverage, and lack of awareness often stand in the way. In Part 2, we’ll break down how to shift the conversation, overcome objections, and use ethical influence to help patients make the best decision for their long-term health. The truth i...
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The Hidden Threat to Dental Implants: Why Ignoring Bacteria is a Risky Gamble – Part 1

    Dental implants are everywhere these days. But you know what else is popping up more often? Implant failures. Here’s the title of a recently promoted CE course: “Peri-Implantitis Badlands: Surviving the Wasteland of Failing Implants” It’s like Einstein said: Doing the same thing over and over and expecting a different result is the definition of insanity. So, when a patient loses teeth due to periodontal disease, why in the world would we expect implants to be immun...
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